Seiji Okada Selected Research

Cytokines

12/2023	The IL-17-IL-17RA axis is required to promote osteosarcoma progression in mice.
1/2023	Cepharanthine inhibits dengue virus production and cytokine secretion.
1/2022	Zinc chelator treatment in crush syndrome model mice attenuates ischemia-reperfusion-induced muscle injury due to suppressing of neutrophil infiltration.
1/2022	Epidural Fat Tissue Is More Effective for Scar Prevention Than Conventional Subcutaneous Fat Grafting After Laminectomy in a Mouse Model.
12/2021	Homophilic Interaction of CD147 Promotes IL-6-Mediated Cholangiocarcinoma Invasion via the NF-κB-Dependent Pathway.
1/2021	Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination.
2/2019	Attenuation of CD47-SIRPα Signal in Cholangiocarcinoma Potentiates Tumor-Associated Macrophage-Mediated Phagocytosis and Suppresses Intrahepatic Metastasis.
2/2016	Proliferation of functional human natural killer cells with anti-HIV-1 activity in NOD/SCID/Jak3(null) mice.
8/2014	Current status of treatment for primary effusion lymphoma.
4/2012	Age-related differences in cellular and molecular profiles of inflammatory responses after spinal cord injury.

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Seiji Okada Research Topics

Disease

87	Neoplasms (Cancer) 05/2024 - 09/2002
32	Cholangiocarcinoma 07/2023 - 06/2010
30	Infections 10/2023 - 09/2009
28	Spinal Cord Injuries (Spinal Cord Injury) 01/2023 - 01/2004
20	Primary Effusion Lymphoma 10/2022 - 09/2009
14	Rheumatoid Arthritis 01/2024 - 12/2018
13	Neoplasm Metastasis (Metastasis) 12/2023 - 04/2012
11	Inflammation (Inflammations) 03/2024 - 07/2002
10	Lymphoma (Lymphomas) 03/2023 - 09/2009
10	Acquired Immunodeficiency Syndrome (AIDS) 10/2016 - 04/2005
9	Congenital Abnormalities (Deformity) 02/2024 - 10/2021
9	Carcinogenesis 12/2023 - 05/2007
8	Pain (Aches) 03/2024 - 04/2012
8	Wounds and Injuries (Trauma) 10/2023 - 04/2008
8	Cicatrix (Scar) 01/2023 - 12/2005
7	Osteoporosis 02/2024 - 10/2021
6	Gliosis 01/2023 - 06/2005
5	Melanoma (Melanoma, Malignant) 01/2018 - 08/2013
5	Ascites 06/2017 - 09/2009
4	Sarcoma (Soft Tissue Sarcoma) 03/2024 - 01/2017
4	Spinal Cord Diseases 12/2023 - 04/2012
4	Hypoxia (Hypoxemia) 01/2023 - 01/2016
4	Fibrosis (Cirrhosis) 01/2023 - 01/2017
4	Leukemia 03/2021 - 08/2007
4	Hematologic Neoplasms (Hematological Malignancy) 01/2016 - 03/2012
3	Multiple Myeloma 03/2024 - 05/2022
3	Postmenopausal Osteoporosis 01/2024 - 10/2021
3	Osteoarthritis 01/2024 - 01/2022
3	Hematoma 01/2024 - 03/2013
3	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2024 - 03/2010
3	Hallux Valgus 08/2023 - 10/2021
3	Hyperglycemia 07/2023 - 10/2014
3	Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated) 04/2023 - 11/2007
3	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2023 - 01/2016
3	Necrosis 01/2023 - 03/2007
3	Squamous Cell Carcinoma of Head and Neck 12/2022 - 02/2015
3	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2022 - 01/2013
3	Breast Neoplasms (Breast Cancer) 01/2021 - 09/2014
3	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2020 - 01/2012
3	HIV Infections (HIV Infection) 09/2018 - 09/2016
3	Disease Progression 01/2018 - 04/2005
3	Lung Neoplasms (Lung Cancer) 01/2017 - 01/2014
2	Spinal Injuries (Spinal Injury) 03/2024 - 01/2023

Drug/Important Bio-Agent (IBA)

18	Proteins (Proteins, Gene)FDA Link 11/2023 - 10/2002
15	CytokinesIBA 12/2023 - 07/2002
8	Therapeutic UsesIBA 01/2024 - 08/2007
7	DNA (Deoxyribonucleic Acid)IBA 03/2024 - 03/2004
7	Transcription Factors (Transcription Factor)IBA 01/2023 - 01/2011
5	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2023 - 07/2012
5	cepharanthineIBA 01/2023 - 09/2009
5	CollagenIBA 01/2023 - 11/2011
5	Interleukin-6 (Interleukin 6)IBA 01/2022 - 06/2005
5	Antineoplastic Agents (Antineoplastics)IBA 05/2019 - 08/2013
5	Liposomes (Liposome)IBA 12/2017 - 03/2010
5	NF-kappa B (NF-kB)IBA 01/2014 - 11/2007
4	CyclodextrinsIBA 11/2023 - 10/2014
4	Folic Acid (Vitamin M)FDA LinkGeneric 11/2023 - 03/2014
4	Messenger RNA (mRNA)IBA 01/2023 - 07/2012
4	Small Interfering RNA (siRNA)IBA 11/2020 - 07/2012
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2016 - 03/2013
4	src-Family KinasesIBA 03/2012 - 04/2005
3	C-Reactive ProteinIBA 03/2024 - 05/2022
3	Biomarkers (Surrogate Marker)IBA 03/2024 - 03/2019
3	romosozumabIBA 01/2024 - 10/2021
3	AntigensIBA 01/2024 - 01/2018
3	Peptides (Polypeptides)IBA 11/2023 - 01/2018
3	Janus Kinase InhibitorsIBA 07/2023 - 01/2022
3	Indicators and Reagents (Reagents)IBA 04/2023 - 08/2015
3	VaccinesIBA 01/2023 - 09/2002
3	ZincIBA 01/2023 - 03/2019
3	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 01/2023 - 06/2005
3	PeriostinIBA 01/2023 - 03/2017
3	Cadherins (E-Cadherin)IBA 01/2023 - 01/2014
3	IntegrinsIBA 01/2023 - 07/2017
3	RNA (Ribonucleic Acid)IBA 01/2023 - 01/2013
3	Monoclonal AntibodiesIBA 10/2022 - 06/2021
3	BerberineIBA 10/2022 - 04/2012
3	Gemcitabine FDA Link 01/2022 - 01/2021
3	AcidsIBA 07/2021 - 03/2020
3	Histones (Histone)IBA 01/2021 - 01/2017
3	Nuclear Proteins (Protein, Nuclear)IBA 10/2020 - 07/2012
3	Janus Kinase 3IBA 01/2019 - 09/2009
3	VimentinIBA 05/2018 - 01/2012
3	Proteasome Endopeptidase Complex (Proteasome)IBA 06/2017 - 09/2013
2	MidkineIBA 03/2024 - 01/2022
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2024 - 06/2021

Therapy/Procedure

33	Therapeutics 01/2024 - 04/2002
14	Transplantation 01/2023 - 01/2004
13	Drug Therapy (Chemotherapy) 08/2023 - 01/2010
8	Osteotomy 01/2024 - 09/2013
7	Activities of Daily Living (ADL) 03/2024 - 12/2017
7	Immunotherapy 01/2024 - 08/2015
5	Arthroplasty 03/2024 - 01/2022
4	Heavy Ion Radiotherapy 04/2023 - 01/2017
4	Decompression 11/2016 - 04/2012
3	Operative Surgical Procedures 12/2023 - 10/2021
3	Cell Transplantation 12/2023 - 01/2004
3	Intraperitoneal Injections 11/2023 - 09/2009
3	Radiotherapy 12/2022 - 01/2017
3	Highly Active Antiretroviral Therapy (HAART) 08/2019 - 03/2010